CKLM syndrome: think of it as an “atomic structure.” Deconstructing Cardiovascular-Kidney-Liver-Metabolic syndrome to its elementary particles…. Nucleus. Core organs — heart, kidney, liver — sit in the nucleus. Three regulatory “orbits” constitute their environment, and define their health. For years, the field has debated brain-centric vs adipocyte-centric models of obesity. Later, with the development of…